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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61256e16fe72a2d9761e5230832f8c8dc8cc7eef0596a43fac15274c7a61059d' 
  AND token = 'iFOsg0WNY89FER42LfRCAoerE07Ibj6WwYTJJsWdb9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}