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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e625ee00d6f4f9c9eb3da687fc03ffcd66dad5f5a97f617dc50baae95a409da8' 
  AND token = 'T7jsdI9mzN7c4U+wCck4BDXwXM1HcpSQUglEKgIxTsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}