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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6fb22c1fb37743498342f4d118839e70f29ec3ba1a61e9902e285772aa9fa0' 
  AND token = 'k+hG7FMp2df2mT2q7ofyPAjJvmEN3pfJcVEfYXn/0ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}