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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c6b5b5cfbca7158fdd726d68d54c41ed2749d0e3594375a0d4ff2e52af8cb6' 
  AND token = 'MocXb9oMhibUsdLtt7fKKXPYBMsPVf4GsIhsA/gnxak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}