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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f07a4c28d5c7567ea054d1c9a83acac8be453427095f8e18a47f8d1e75838f' 
  AND token = 'J2L5zOIWKKWC/EiCKcZQ6zlhV6Ud42J8m9mUxzAgHj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}