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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222689837cb12c607b44cb17936ca9abc0576610a12e4e44fe40822084866524' 
  AND token = 'ATDau6Tzb5Z1JxDd5bVqvLpLsQUqOokBjvURhPsYIL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}