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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5bbade377702a3fea1765f18f32309d415fd34b04b3ce6e69ff5164aacc77a' 
  AND token = 'UrNRWL2/31RYO9+VZ05DnH98/35rPN/0iNWGSUuo97k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}