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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '964c055fef6e39e8e54961306936191067cbd53f88c8eaf5abf25a1441a87455' 
  AND token = '/d/4WZxHS2qoAPn7KaEJty3nTRs47RWEYAAKjpId9AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}