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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff1bbfb5e9aa553a5a14c5f3bf5e4473acf09d4844e8774670691cad05b33bc8' 
  AND token = 'AD743+BxTpCGmOCKIBrnlUgSj4E3nYuo1tuXG/9RirY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}