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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e7dde913f5aa5aa16f39f6c9affef930cb4be616ad1f74d96bf94fd741aa8d0' 
  AND token = 'wiTmIpeo7dazgqrr3l0Np7G6EYiiYTLlca50RLQ6kTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}