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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '307001250d12a01094d00f6bc8008d9187f34466faa0a8e945d9aa205ce8ae4d' 
  AND token = 'pXr7Ad9gOkqsliTXlN3p2KhavPidZfQho0NUFWyZS5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}