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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21684e3d45e9a1db8e07440d61e1d3c84ad8ff3a32e63b755b3916b287d63ef9' 
  AND token = 'Ultce52cc2GOgkE6YEcvky/redLNSk3Tj70IISTl/uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}