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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7da6254ad31905dce4f767f08671b4181cedfe3fcdc30e8d4d1441ed6f8c441' 
  AND token = '5D2GS1eEwFqQpbbzTxRRwutyfkYH9xetG/u0WfIjwdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}