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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d16dc9c9114500aa64829e40772fdbf3be2ca7d4cc8f50faadb7d66005995b3' 
  AND token = 'aMjOGEhcItYrfkHvebiOoRE2/eU70omjVfu3RpF56Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}