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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a0a351dfa5729247f2fd4dcdaa2276206f56eb899a46e11a00af235bc4caa4' 
  AND token = 'QBUx1nh8O+cQBGt+v9utaBK4IPxTm/xaqpEgoQhi8Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}