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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1953371d166f9ffb306afde2d00adf3384dc9945ae9a3480da6cd010d6136e40' 
  AND token = 'dCq7+q9Ne6X5jhIwwiRxTrPdRrAnkV/E8d3EWDoyqc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}