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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a3516b488d9902fbcf08080b49a9baaf180daea60a3d360fb9b50d74f56311' 
  AND token = 'Dc8xdzEHm4nEOm/UtWINUDDHLJngLp80LSaEyWsva4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}