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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6713aefacf9a27ba95ae6d8b00fc77c3e31a182e9111c6f6c344fc1de74c450a' 
  AND token = 'd4I4cVhrizXzsf+G9N0L+h+NKlhmaSl+yD0QviqxR68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}