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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53045fc5f5929cb193a302d16cbefb2c63a0c0f415e6e00a020eaaf81766b8bf' 
  AND token = '1onD1MhTmv4MOt7lM9F+HCICJjOJQGHiRglkqEb7MpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}