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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6296c843faf1002140c7ee863d0c806cb2b8f1cccb5a8901270557dfc3d6d79f' 
  AND token = '7JRQlhNxMaruvWeAb2v1xC6z8OhjlBKPNfxIc0P46zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}