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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8633907f63152b4a4c7eff7bc1946756c5201a0d1d29e90afe6ab6aa30806bb4' 
  AND token = 'XrECZ6H+RY9dXWoiriHW4ZzLHkeYYDGz35hPFWIDa7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}