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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4cf0fe993f25f8cde6d0ccc85b6023c153145fb5139a76c7b130ec6377365b' 
  AND token = 'cTIT/kW9DtpOEdiH4BVoICJGDeA2LeCIDj5cLlOVpAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}