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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ce90aa6cac090d183fdcdd7642926aeedd460853cc3127b57e1ea95710faf9' 
  AND token = 'VaK8JvBY8QA0ehjtA/SWQZ+mibRBvY6JicmZk1N7SHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}