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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec503856d9d8ae299061d936c016f34040148a9dce8b3cbf3c8fb3a6dae0079' 
  AND token = 'QUCcZfIefUK2+Bncs/aEJ5C5PuVyiLXfmyWgUjJXqCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}