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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e6e4a05ccb8a9be61a5d00ee8cf68c274feaba01da4d7a4f268dfd7f33253eb' 
  AND token = 'mQYBNoDZrhDZxfOsN/SP6ruWscqhwOJvLNJKLwbSdAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}