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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e0169e6d5ee5088434b61703b8fddaa99c42480b5f872525d817d83b8281f5' 
  AND token = 'ssOcHAgT3wli6GdgP/lUxMtdfogyheecJ/QP+pRFH0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}