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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39f7ed175947d489ed745757d6bc13f2870a1f3ac2bf90ceaf9b5eace9376cb' 
  AND token = 'gETK+Mt/wlv+LOfNQxQSP4sL181GVt7UXL/yf41IlEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}