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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae63ce54501180237b4ebba0cf3a62a35c34ae70daba7fec82b31e71412891f' 
  AND token = 'nNMn9LL/TC63+BH730fQy08871DhXXnZtYcwFQiO6dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}