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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ebd2e40682055ff798bfed97750a3127c847ca5f48f3910d2df32c12dc50ee' 
  AND token = 'Lknssh0SqfBVADPO1kQtyn+zxvIPSXjW7fZgMkE3gyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}