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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b3514fe8da93ff777f1f8c4ca027d7742a7fedec71d75bb7648ac4ef9bfd61' 
  AND token = 'VPKXqSRguXja+dfzvRMqQhnZivxIdDWay4Oy1yV2KEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}