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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce81698dcea03b646d9248eb037c5ba28d565779c8029e7fbf2e2a22c70671df' 
  AND token = '++PFP6IVnDPvxwv8r4Lq9UdC76nY81xckKmUUe22MK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}