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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36f21a936a95239d6033c27d73cf82e8b1c8da78ff00291deb2f22509c8d9eab' 
  AND token = '7GOiwMFlOF3kipiF0waBQ0TuD1MFb2TW646Zc0AWb/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}