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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e59e425ffe665d91b24c3a25c20c1def45e916b970c22733d642dfae3f87de' 
  AND token = 'H54fIpkn0voX9iIwDfkkyiF6fPl3/9e3VRpooXkP5ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}