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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed603c6d3fca83ab8175d1270066dfa516b3f78133fab3b44784e96f2fb949d5' 
  AND token = 'keSGLnXsLeqqI2qZI+iXQ8+QQlzmNZ722QUlT5+bnDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}