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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c86fbf4c7b0d2c3171a6ec03211dd7b5244294a66ec469dbc1afcf3e3d15fb71' 
  AND token = 'vbpaap10L9wKq8mjQVzWpEkEeJyK8NstlrkPUFwevpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}