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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d680b3900af39c9a828d85643b6bb1796235e9ec7cc739e8a8e4db674d3e8e1' 
  AND token = 'S/RZH2cevQ1Y5U9Seek5VODcQxXkZYa9zc451V2pb3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}