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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ffad10111a5ac0c2d1a065f2384a696a9684f6849635e39d1ec62ef004d8b2' 
  AND token = 'aZJz2SJ28SXA35ycco5PsMFOSUbUpOx1+6Q3vbDLYK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}