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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0309c0b1098cf4732701d95ff6384badc3395d408e925ff6f8ae4e9c3276109' 
  AND token = 'FMr5IvBmvRRuUe0DZtuNHnzMo6GfxMw7Szu7FsyGw/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}