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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78569c5789642f68afc7cb0766ff04a733fcc4c5ace9ba3a4490a9b34aab661' 
  AND token = 'KaUL5FIT0l4CVkwSrklFYvPAcL3vTmeW9gDilXIjh0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}