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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389b8529073f59e040fff6bb6168766b9bdea49601defe37e77365d9129178ae' 
  AND token = 'ivKwrza6zUHjtRaw/iUAJn4kgjat629P9uitnbp8RbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}