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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1945f283e6427588f285f761b51de20bddd7e8f4ed3372180bc2469242792af1' 
  AND token = 'gWAqq641xpG2J+9vx9mJd64a7wrQiXx0o7NMxl/a3v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}