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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3eea2654ac5f04a70badefc80a013f8a478c83fa3dcd7faf6b9621ca125829' 
  AND token = 'xWCteKrhnZweaP9yEGtbo9syXc/z3xmA3iWvvHkW+H0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}