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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41703bdf9df117f68c73e653d8a602901f38cd865714de0d8f83ceeea4cc39dc' 
  AND token = 'eScqEaO9T/epvyPWfeyG0p4zexJf/krrdRqn91orZd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}