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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81008cee7aa83c68e34c9ee87742b914ee27f9206ebca7afde31e7b5bddb9c6c' 
  AND token = 'hkmE5+ZROlGuc9SufDATAT7g6QZt7Zgs98lMbmiwkYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}