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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe04bc1bb2ec8688d99e0f20c47cba875a98d967d37e4b6f750e120a523b934' 
  AND token = 'qdKA+IzmTs4Wd8ewg/9wMk43ZhodxY5/2aZ7QZwKZRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}