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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49093185e598475d2a2ac74997fc499911b6f5bc5a55c29fb363353e53ca3b5f' 
  AND token = '6fDqnAUYqHQMeHRaWuLwXMR3mN72QZp1dZUc580YjAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}