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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b59e592c4921d0db9e71a2e26b59ba3ecae9526d598547e1dbbbe2ec0eacbf' 
  AND token = 'emkBJu1w074lxVXHt/GAakOwNLFbAhcQslXka59HCaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}