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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464a72982d7a0a592d01e3e21b1c607f018e498c23357fb9a319937c71dd07df' 
  AND token = 'Cx6p0cXQnTlmqOr6aMxqbXayAxUppAkEJ9D6i7egR5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}