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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d5c946c5277711fcd91ea5fafaa7de3971fc2767a72e2acbe08d8d090c6867' 
  AND token = 'dk4XfwrMWhHXCJUAJ5D+ar3HbwJ9MQ2Viz7sU204W/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}