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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280adc5028961d842922ba9cb296d7a07867663c44640ff42da98f83adcbfe16' 
  AND token = '0g+A85b1IMMWLXU4IBcqCIidsSBWCdJVKX9nT0DeQUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}